[Seite 1]
Anhang A
Stoffliste
Im Rahmen der Screeningarbeiten (AP1) ist das Vorliegen der folgenden Additive bzw. Analyten, im Folgenden „Stoffe“ genannt, und Stoffgruppen zu untersuchen:
Chlorparafne: Additive aus der Gruppe der kurzkettigen (SCCPs), mittelkettigen (MCCPs) und langkettigen (LCCPs) Chlorparafne Thiourea (EC: 200-543-5, CAS: 62-56-6, CLP harmonisierte Einstufung: Carc. 2) und weitere Verbindungen der Summenformel S=C(NR ) , R = organischer 22 Rest Heteroaromaten: 2-Mercaptobenzothiazol (EC: 205-736-8, CAS: 149-30-4, CLP harmonisierte Einstufung: Skin Sens 1) und weitere heteroaromatische Stoffe Amine1: N-1,3-Dimethylbutyl-N'-phenyl-p-phenylendiamin (6PPD) und verwandte Stoffe der Gruppe Phenyl-p-phenylendiamine (PPDs) und para- substituierten Phenylendiamine (PDs), wie: para-Phenylendiamin (auch bekannt als Benzol-1,4-diamin, 1,4-Diaminobenzol und 1,4-Phenylendiamin) sowie alle seine Derivate, die:
• einen oder zwei Substituenten an einem oder beiden (P)PD-Stickstoffatomen aufweisen • keine zusätzlichen Substituenten oder Modikationen am (P)PD-Phenylring an den Positionen 2, 3, 5 oder 6 enthalten • an keinem der beiden (P)PD-Stickstoffatome Stickstoff-Stickstoff-Doppelbindungen oder Stickstoff-Stickstoff-Dreifachbindungen enthalten • an keiner Stelle im Molekül quaternäre Amine (d. h. quaternäre Ammoniumkationen) enthalten
Tab. 1:Stoffliste
| lfd. Nr. | Stoffname | EC | CAS | CLP_HARM_EINSTUFUNG EN | SELBSTEINSTUFUNGEN | STOFFGRUPPE_NAME | ||
|---|---|---|---|---|---|---|---|---|
| 1 | Mittel- und kurzkettige | divers | divers | divers | divers | Chlorparaffine | ||
| Chlorparaffine | ||||||||
| 2 | Thiourea | 200-543-5 | 62-56-6 | Carc. 2, Repr. 2, Acute Tox. 4 | Carc. 2, Repr. 2, Acute Tox. 4 | Verbindungen der Summenformel S=C(NR ) , R = 2 2 organischer Rest |
1 Siehe dazu auch: https://echa.europa.eu/documents/10162/9712f930-ae31-cfde-13f5-95227842e88c
[Seite 2]
Anhang A
| 3 | 2-Mercaptobenzothiazol | 205-736-8 | 149-30-4 | Skin Sens 1 | Skin Sens 1 | Heteroaromatische | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Verbindungen | ||||||||||||||||||||
| 4 | N-1,3-dimethylbutyl-N'-phenyl- p-phenylenediamine | 212-344-0 | 793-24-8 | NA | Acute Tox. 4, Aquatic Acute 1, Aquatic Chronic 1, Repr. 1B, Skin Sens. 1 | amino-substituted diarylamines, Phenyl-p- phenylendiamine | ||||||||||||||
| 5 | N-(1,4-dimethylpentyl)-N'- phenylbenzene-1,4-diamine | 221-374-3 | 3081-01-4 | NA | Repr 1B, Skin Sens 1 | amino-substituted | ||||||||||||||
| diarylamines, | ||||||||||||||||||||
| Phenyl-p- | ||||||||||||||||||||
| phenylendiamine | ||||||||||||||||||||
| 6 | 1,4-Phenylendiamin | 203-404-7 | 106-50-3 | Acute Tox. 3, Skin Sens 1 | Acute Tox. 3, Skin Sens 1 | Phenyl-p- phenylendiamine und para-substituierten Phenylendiamine | ||||||||||||||
| 7 | N,N-diethylaniline | 202-088-8 | 91-66-7 | Acute Tox. 3, Aquatic Chronic 2, STOT Rep. Exp. 2 | Acute Tox. 3, Aquatic Chronic 2, STOT Rep. Exp. 2, Skin Irrit. 2 | n-alkylated anilines | ||||||||||||||
| with any number of | ||||||||||||||||||||
| alkyl chains and amine | ||||||||||||||||||||
| group substituents on | ||||||||||||||||||||
| the phenyl ring | ||||||||||||||||||||
| 8 | N,N-dimethyl-p-toluidine | 202-805-4 | 99-97-8 | Acute Tox. 3, Acute Tox. 4, Aquatic Chronic 3, Carc. 1B, STOT Rep. Exp. 2 | Acute Tox. 2, Acute Tox. 3, Aquatic Chronic 3, Carc. 1B, Repr. 2, STOT Rep. Exp. 2, Skin Sens. 1 | n-alkylated anilines with any number of alkyl chains and amine group substituents on the phenyl ring | ||||||||||||||
| 9 | 2,2',2''-nitrilotriethanol | 203-049-8 | 102-71-6 | NA | Eye Damage 1, Repr. 2 | triethanolamines | ||||||||||||||
| 10 | Melamine | 203-615-4 | 108-78-1 | Carc. 2, STOT Rep. Exp. 2 | Carc. 2, Repr. 2, STOT Rep. Exp. 2 | 1,3,5-triazine- 2,4,6(1h,3h,5h)-trione and 1,3,5-triazine- |
[Seite 3]
Anhang A
| 2,4,6-triamine derivatives | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| 11 | Diphenylamine | 204-539-4 | 122-39-4 | Acute Tox. 3, Aquatic Acute 1, Aquatic Chronic 1, STOT Rep. Exp. 2 | Acute Tox. 3, Aquatic | substituted diphenylamines | ||||
| Acute 1, Aquatic Chronic | ||||||||||
| 1, Carc. 2, Eye Irrit. 2, | ||||||||||
| STOT Rep. Exp. 2 | ||||||||||
| 12 | Octadecylamine | 204-695-3 | 124-30-1 | Aquatic Acute 1, Aquatic Chronic 1, Asp. Tox. 1, Eye Damage 1, STOT Rep. Exp. 2, Skin Irrit. 2 | Aquatic Acute 1, Aquatic Chronic 1, Asp. Tox. 1, Eye Damage 1, STOT Rep. Exp. 2, Skin Irrit. 2 | aliphatic primary amines | ||||
| 13 | 2-aminoethanol | 205-483-3 | 141-43-5 | Acute Tox. 4, Skin Corr. 1B | Acute Tox. 3, Acute Tox. | monoethanolamines | ||||
| 4, Aquatic Chronic 3, Eye | ||||||||||
| Damage 1, Repr. 2, Resp. | ||||||||||
| Sens. 1, STOT Single Exp. | ||||||||||
| 3, Skin Corr. 1B, Skin | ||||||||||
| Sens. 1 | ||||||||||
| 14 | diuron (ISO), 3-(3,4- dichlorophenyl)-1,1- dimethylurea | 206-354-4 | 330-54-1 | Aquatic Acute 1, Aquatic Chronic 1, Carc. 1B, STOT Rep. Exp. 2 | Acute Tox. 4, Aquatic Acute 1, Aquatic Chronic 1, Carc. 2, STOT Rep. Exp. 2 | chlorophenyl ureas and chlorophenyl amines | ||||
| 15 | 1,3,5-triazine-2,4,6(1H,3H,5H)- trione, compound with 1,3,5- triazine-2,4,6-triamine (1:1) | 253-575-7 | 37640-57-6 | NA | Carc. 2, Repr. 2, STOT Rep. Exp. 2 | 1,3,5-triazine- | ||||
| 2,4,6(1h,3h,5h)-trione | ||||||||||
| and 1,3,5-triazine- | ||||||||||
| 2,4,6-triamine | ||||||||||
| derivatives | ||||||||||
| 16 | Benzenamine, N-phenyl-, reaction products with 2,4,4- trimethylpentene | 270-128-1 | 68411-46-1 | NA | Aquatic Chronic 3, Carc. 2, Repr. 2 | substituted diphenylamines |
[Seite 4]
Anhang A
| 17 | 1,4-Benzenediamine, N,N'-mixed Ph and tolyl derivs. | 273-227-8 | 68953-84-4 | Repr. 1B, Skin Sens. 1 | Aquatic Acute 1, Aquatic | amino-substituted diarylamines | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Chronic 1, Repr. 2, Skin | ||||||||||||
| Sens. 1B | ||||||||||||
| 18 | Diphosphoric acid, compound with 1,3,5-triazine-2,4,6-triamine | 239-590-1 | 15541-60-3 | NA | Aquatic Chronic 3, Eye Irrit. 2, STOT Rep. Exp. 2 | 1,3,5-triazine- 2,4,6(1h,3h,5h)-trione and 1,3,5-triazine- 2,4,6-triamine derivatives | ||||||
| 19 | Di(µ-2,2´,2´´-nitrilotris(ethanol)- | 480-340-8 | 156157-97-0 | NA | Eye Damage 1, STOT | triethanolamines | ||||||
| diperchlorato)dinatrium | Rep. Exp. 2, Unst. Expl. | |||||||||||
| 20 | Amines, N-(C16-18 (even numbered) and C18-unsatd. alkyl) trimethylenedi-, ethoxylated(NLP) | 800-029-6 | 1290049-56- 7 | NA | Acute Tox. 4, Aquatic Acute 1, Aquatic Chronic 1, Eye Damage 1, STOT Rep. Exp. 1, Skin Corr. 1B | ethoxylated n- alkyltrimethylenediami nes | ||||||
| 21 | N-Phenyl-1-naphthylamine | 201-983-0 | 90-30-2 | NA | Acute Tox. 4, STOT Rep. | NA | ||||||
| Exp. 2, Skin Sens. 1B | ||||||||||||
| 22 | Anilin | 200-539-3 | 62-53-3 | Acute Tox. 3, Aquatic Acute 1, Carc. 2, Eye Damage 1, Muta. 2, STOT Rep. Exp. 1, Skin Sens. 1 | Acute Tox. 3, Aquatic Acute 1, Aquatic Chronic 1, Carc. 2, Eye Damage 1, Muta. 2, STOT Rep. Exp. 1, Skin Sens. 1, Skin Sens. 1B | aromatic primary monoamines | ||||||
| 23 | N-1-methylheptyl-N'-phenyl-p- phenylenediamine | 239-281-1 | 15233-47-3 | Acute Tox 1, Skin Sens. 1, | NA | |||||||
| Aquatic Acute 1, Aquatic | ||||||||||||
| Chronic 1 (PubChem) | ||||||||||||
| 24 | p'-(p- Toluenesulfonylamido)diphenyla mine (4'-anilinotoluene-4- sulphonanilide) | 202-902-1 | 100-93-6 | Acute Tox. 4 (PubChem) | Skin Sens. 1 | NA |
[Seite 5]
Anhang A
| 25 | Benzoguanamin | 202-095-6 | 91-76-9 | Acute Tox. 4, Aquatic | Acute Tox. 4, Effect on or | NA | ||||
|---|---|---|---|---|---|---|---|---|---|---|
| Chronic 3 | via lactation, Repr. 1B | |||||||||
| 26 | 2,2,6,6-Tetramethylpiperidin-4- ol | 219-291-2 | 2403-88-5 | NA | Skin Sens. 1A, Skin Corr. 1C, Eye Damage 1, Skin Sens. 1, Acute Tox. 4, Skin Corr. 1B | NA | ||||
| 27 | 1,3-diphenylguanidine | 203-002-1 | 102-06-7 | Repr. 2, Acute Tox. 4, STOT | Acute Tox. 3, Acute Tox. | n,n'-diphenylguanidine derivatives, | ||||
| Single Exp. 3, Skin Irrit. 2, | 4, Eye Damage 1, Eye | |||||||||
| Eye Irrit. 2, Aquatic Chronic | Irrit. 2, Repr. 2, Skin Irrit. | |||||||||
| 2 | 2, STOT Single Exp. 3 | |||||||||
| 28 | Benzimidazole-2-thiol | 209-502-6 | 583-39-1 | NA | Acute Tox. 3, Skin Sens. 1, STOT Rep. Exp. 2 | benzimidazolethiones | ||||
| 29 | N-Phenyl-2-naphthylamine | 205-223-5 | 135-88-6 | Aquatic Chronic 2, Carc. 2, | NA | NA | ||||
| Eye Irrit. 2, Skin Irrit. 2, Skin | ||||||||||
| Sens. 1 |